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Lesson

Systems integration

How cellular changes propagate to tissue and organ-level effects.

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Lesson Notes
Section 1 / 10

Systems integration is the MCAT's favorite reasoning skill. You must connect a molecular or cellular change to a tissue effect, then to an organ, then to a system-level outcome. This is how passages turn basic biology into clinical reasoning.

Short segments for focus-friendly pacing.
Key Points
  • Systems are built from cell-to-tissue organization
  • Homeostasis links multiple systems
  • System outcomes follow a chain of effects
  • Identify the most dependent tissue first
  • Avoid answers that skip steps
Reflection

Choose a cellular defect (ion channel, enzyme, receptor). Write the tissue it affects and one system-level symptom you would expect.

Quick Check
Which reasoning chain is most consistent?
Why does the MCAT emphasize systems integration?
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External Links
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Khan Academy® MCAT (External)

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