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Lesson

Enzymes and regulation

Enzyme kinetics, inhibition types, and pathway control.

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Lesson Notes
Section 1 / 12

Enzymes control speed. The MCAT uses enzymes to test your ability to reason about rate changes, inhibition, and pathway consequences. You must explain why a reaction accelerates or slows, not just name the enzyme. If you can predict what builds up, what drops, and how a cell compensates, you can solve most enzyme passages.

Short segments for focus-friendly pacing.
Key Points
  • Enzymes lower activation energy, not equilibrium
  • Competitive inhibition affects Km more than Vmax
  • Non-competitive inhibition lowers Vmax
  • Feedback loops regulate pathway output
  • Predict substrate and product shifts when a step is blocked
Reflection

Think of a pathway you know. If the final product doubled, how would feedback inhibition change the earlier steps? Write a two-sentence explanation.

Quick Check
Which inhibitor type can be overcome by increasing substrate?
If enzyme X is inhibited, what happens to the substrate immediately before X?
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